Mutation Strain Type
|Institution name||Depositor / Originator||Name|
Mice express membrane tethered human TFPI-CD4 fusion protein on all alpha-SMA+ (alpha smooth muscle actin) cells. In cells with secretory granules, these will be internalised at resting state by virtue of P-selectin cytoplasmic sequence. The hTFPI (human tissue factor pathway inhibitor)inhibits tissue factor and FXa (factor Xa).