Title Phenotype Contact
129(B6)-Apoe<tm1Bres> Plat<tm1Mlg>/CljH[cc]
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:2137814 Apoe<tm1Bres> MGI:88057 Apoe
MGI:1857288 Plat<tm1Mlg> MGI:97610 Plat
None. Contact
129(B6)-Apoe<tm1Bres> Plg<tm1Jld>/CljH[cc]
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:2137814 Apoe<tm1Bres> MGI:88057 Apoe
MGI:1857291 Plg<tm1Jld> MGI:97620 Plg
Rectal prolapse. Shortened life span in homozygotes. Contact
129(B6)-Serpine1<tm1Mlg> Apoe<tm1Bres>/CljH[cc]
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:2137814 Apoe<tm1Bres> MGI:88057 Apoe
MGI:1857287 Serpine1<tm1Mlg> MGI:97608 Serpine1
Shortened life span. Contact
129(B6)-Thy1<tm1Rjmo>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:3586862 Thy1<tm1Rjmo> MGI:98747 Thy1
Nervous system: reduced long term potentiation (J:31610). Strong inhibition of LTP in the dentate gyrus but not in CA1, however spatial learning as assessed in the watermaze is unimpaired. Respiratory system: pulmonary fibrosis (J:99951). Marked increase in severity of lung fibrosis and more extensive collagen deposition in response to intratracheal bleomycin, compared to controls. Contact
129(Cg)-Tecta<tm5.1Gpr>/GprH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5527096 Tecta<tm5.1Gpr> MGI:109575 Tecta
In Tecta<tm5.1Gpr>/<tm5.1Gpr> homozygotes the tectorial membrane is completely detached from the spiral limbus and is associated instead with the Reissner membrane. Tecta is virtually undetectable by immunofluorescence in the detached tectorial membrane, with the exception of some weak labelling at the extreme apical end. In heterozygous mice inner ear phenotype shows malformation of the tectorial membrane, ABR thresholds elevated by ~35 dB and an enhanced susceptibility to audiogenic seizure at low sound pressure levels. See PubMed 24363064 Legan et al Human Mol Genet 2013: Three deaf mice. Contact
129-Ctsg<tm1.1Roes>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:2182170 Ctsg<tm1.1Roes> MGI:88563 Ctsg
Mice deficient in Ctsg are susceptible to fungal infections, despite normal neutrophil development and recruitment. Contact
129-Elane<tm1(cre)Roes>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:2182177 Elane<tm1(cre)Roes> MGI:2679229 Elane
Homozygotes have impaired neutrophil recruitment and impaired innate immunity. Contact
129-Elane<tm1(cre)Roes>Ctsg<tm1.1Roes>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:2182177 Elane<tm1(cre)Roes> MGI:2679229 Elane
MGI:2182170 Ctsg<tm1.1Roes> MGI:88563 Ctsg
Impaired innate immunity. Contact
129-Epc1<tm1e(EUCOMM)Wtsi>/WtsiH
Allele MGI ID Allele Name Gene MGI ID Gene Name
              MGI:1278322 Epc1
To see phenotype data (when available) visit www.mousephenotype.org IMPC report a range of phenotypes for the tm1a allele, however these data should probably be assigned to the tm1e allele. Phenotypes include: decreased body weight, increased lactate dehydrogenase level, abnormal coping response, abnormal bone mineralization, increased circulating creatine kinase level & increased mean corpuscular volume. Contact
129-Foxa2<tm1Jrt>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:1857725 Foxa2<tm1Jrt> MGI:1347476 Foxa2
Homozygous lethal at day 8 of gestation. This mouse strain has a pre-disposition to develop mis-aligned jaws which leads to over grown teeth. Contact
129-Ncf1<tm1Hbd>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:3576788 Ncf1<tm1Hbd> MGI:97283 Ncf1
Impaired innate immunity. Contact
129-Tgfbr2<tm1Roes>/RoesH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:3045693 Tgfbr2<tm1Roes> MGI:98729 Tgfbr2
Contact
129.C-Tg(Prnp/PRNP)1Drb 129-Prnp<tm1Cwe>/DrbH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:1888773 Prnp<tm1Cwe> MGI:97769 Prnp
The octameric repeat region of the mouse prion protein was replaced with the hexameric repeat region from the domestic chicken. The mice express mouse PrP at wild-type levels with correct membrane location and orientation but have an altered metal binding region. The mice have been generated to get a better understanding of prion diseases such as CJD in humans. Contact
129.Cg-Pax6<Sey> Tg(Hbb-b1)83Clo/WsH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:1856155 Pax6<Sey> MGI:97490 Pax6
MGI:2655271 Tg(Hbb-b1)83Clo              
Reiterated transgene is detectable by DNA in situ hybridisation. Contact
129.Cg-Tg(TetO-Gal)82Wyn/WynH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:5554441 Tg(TetO-Gal)82Wyn MGI:5554440 Tg(TetO-Gal)82Wyn
Homozygotes have a reduction in neuropathic pain. Contact
129.Cg-Tgm2<tm1Gml> Apoe<tm1Bres>/CljH[cc]
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:2137814 Apoe<tm1Bres> MGI:88057 Apoe
MGI:2180638 Tgm2<tm1Gml> MGI:98731 Tgm2
None. Contact
129P2-Gal<tm1Wyn>/WynH
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:2183172 Gal<tm1Wyn> MGI:95637 Gal
Developmental deficits in DRG and cholinergic neurons, absence of neuropathic pain, deficits in neuronal regeneration and neurite outgrowth and more severe disease in EAE model of MS and A-beta model of AD Contact
129P2/OlaHsd-Dynll1<Gt(EUCE0287d04)Hmgu>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:4368846 Dynll1<Gt(EUCE0287d04)Hmgu> MGI:1861457 Dynll1
View available phenotyping data on the IMPC portal Contact
129P2/OlaHsd-Mkrn1<Gt(RRB087)Byg>/H View available phenotyping data on the IMPC portal Contact
129P2/OlaHsd-Rab18<Gt(EUCE0233a03)Hmgu>/H
Allele MGI ID Allele Name Gene MGI ID Gene Name
MGI:4369232 Rab18<Gt(EUCE0233a03)Hmgu> MGI:102790 Rab18
Full phenotype description is available on the IMPC portal (www.mousephenotype.org) Contact

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