Stock STOCK Mut1139/H

Stock Name

MUT1139

FESA Number

1352

Strain Name

STOCK Mut1139/H

Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Radiation induced mutation IMSR - unclassified

Attribution

Mother Genotype

3H1

Father Genotype

Mut1139/+

Colony Stock Code

MUT1139

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome Is Background
Mut1139 MGI:5439937 Mut1139 MGI:5439942

phenotype_terms

MP:0000585
MP:0000592
MP:0011568
MP:0001265

Phenotypic Description

Heterozygotes: shortened kinky tail with white feet. Breeding data indicate that penetrance is variable: circa 90% on crosses of 3H1 males to Mut1139/+ females, but lower from the reciprocal matings. No affected pups (out of 42 scored) were seen from Mus castaneus females x Mut1139/+ males. Viability of affected pups to weaning is good (over 80% survival recorded from above 3H1 crosses. Weight data are variable, but indicate that Mut1139/+ are smaller on average (circa 20%) than normal littermates at birth and weaning. Homozygotes: opening data strongly suggest death by early post implantation. Mapping: shown not to be an allele of T, nor a deletion encompassing tf or qk. No evidence of linkage with ma, Tyrp1<b> or Bmp5<se>. Taking data from pups showing Mut1139/+ phenotype only: suggestion of linkage to Egfr<wa2> (11 recombinants out of 32 pups). Cytogenics: no obvious chromosomal aberration detected.

Publications

Displaying 1 - 1 of 1 Stock Publications
Pubmed ID Authors Title Journal
MouseBookTM Information obtained from MouseBook<sup>TM</sup>, Medical Research Council Mammalian Genetics Unit, Harwell, UK. Unpublished (2 005) :

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Homozygous Mice Viable

Homozygous Mice Fertile

Immuno-Compromised