Stock B6.Cg-Syce2<Gt(FHCRC-GT-S8-7E1)Sor>/H

FESA Number

3552

Strain Name

B6.Cg-Syce2<Gt(FHCRC-GT-S8-7E1)Sor>/H

Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Gene Trap IMSR - mutant strain

Attribution

Institution name Depositor / Originator Name
MRC Human Genetics Unit Originator Retained
MRC Human Genetics Unit Depositor Retained

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Syce2<Gt(FHCRC-GT-S8-7E1)Sor> MGI:3708176 Syce2 MGI:1919096 8

Phenotypic Description

Mice homozygous for this mutation in this background can not progress to diplotene stages of meiosis and show a failure of synapsis. Heterozygous mice show close to normal fertility.

Publications

Displaying 1 - 2 of 2 Stock Publications
Pubmed ID Authors Title Journal
17339376 Bolcun-Filas E SYCE2 is required for synaptonemal complex assembly, double strand break repair, and homologous recombination. J Cell Biol (2 007) 176:741-7
21478856 Daniel K Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1. Nat Cell Biol (2 011) 13:599-610

EMMA ID

EM:04537

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