Stock B6.Cg-Syce1<tm1Hgu>/H
FESA Number
3553
Strain Name
B6.Cg-Syce1<tm1Hgu>/H
Mutation Strain Type
| Mutation Type | Mutation Subtype | Strain Type |
|---|---|---|
| IMSR - Targeted mutation | IMSR - mutant strain |
Attribution
| Institution name | Depositor / Originator | Name |
|---|---|---|
| MRC Human Genetics Unit | Originator | Retained |
| MRC Human Genetics Unit | Depositor | Retained |
Gene/Allele Information
| Allele Name | Allele MGI ID | Gene Name | Gene MGI ID | Chromosome |
|---|---|---|---|---|
| Syce1<tm1Hgu> | MGI:3840564 | Syce1 | MGI:1921325 | 7 |
Phenotypic Description
Mice homozygous for this mutation in this background can not progress to diplotene stages of meiosis and show a failure of synapsis. Heterozygous mice show close to normal fertility.
Publications
Displaying 1 - 1 of 1 Stock Publications
| Pubmed ID | Authors | Title | Journal |
|---|---|---|---|
| 19247432 | Bolcun-Filas E | Mutation of the mouse Syce1 gene disrupts synapsis and suggests a link between synaptonemal complex structural components and DNA repair. | PLoS Genet (2 009) 5:e1000393 |
EMMA ID
EM:04538
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