Stock B6.129S6-Rhbdf2<tm1.1Mfm>/H

FESA Number

3462

Strain Name

B6.129S6-Rhbdf2<tm1.1Mfm>/H

Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Targeted mutation IMSR - unclassified

Attribution

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Rhbdf2<tm1.1Mfm> MGI:5309177 Rhbdf2 MGI:2442473 11

Orphanet Disorders

OrphaNet ID Name Url
2 198 Palmoplantar keratoderma-esophageal carcinoma syndrome http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=2198

Publications

Displaying 1 - 3 of 3 Stock Publications
Pubmed ID Authors Title Journal
22246777 Adrain C Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE. Science (2 012) 335:225-8
23969955 Christova Y Mammalian iRhoms have distinct physiological functions including an essential role in TACE regulation. EMBO Rep (2 013) 14:884-90
Mouse Genome Informatics and the Europhenome Mouse Phenotyping Resource Obtaining and Loading Phenotype Annotations from Europhenome Database Release (2 010) :

Orphanet Categories

Rare gastroenterologic disease
Rare skin disease

Background Strain Name

C57BL/6J

Background Strain MGI ID

MGI:3028467

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