Stock B6.129P2-Psip1<Gt(betageo)1Hgs>/H
FESA Number
3770
Strain Name
B6.129P2-Psip1<Gt(betageo)1Hgs>/H
Mutation Strain Type
| Mutation Type | Mutation Subtype | Strain Type |
|---|---|---|
| IMSR - Gene Trap | IMSR - unclassified |
Attribution
| Institution name | Depositor / Originator | Name |
|---|---|---|
| MRC Human Genetics Unit | Originator | Retained |
| MRC Human Genetics Unit | Depositor | Retained |
Gene/Allele Information
| Allele Name | Allele MGI ID | Gene Name | Gene MGI ID | Chromosome |
|---|---|---|---|---|
| Psip1<Gt(betageo)1Hgs> | MGI:3664569 | Psip1 | MGI:2142116 | 4 |
Phenotypic Description
Perinatal lethal, homozygotes have homeotic transformations and abnormal ribcage.
Publications
Displaying 1 - 2 of 2 Stock Publications
| Pubmed ID | Authors | Title | Journal |
|---|---|---|---|
| 22615581 | Pradeepa MM | Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing. | PLoS Genet (2 012) 8:e1002717 |
| 16980622 | Sutherland HG | Disruption of Ledgf/Psip1 results in perinatal mortality and homeotic skeletal transformations. | Mol Cell Biol (2 006) 26:7201-10 |
EMMA ID
EM:04660
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