Stock B6.129P2-Grin1<tm2Slab>/H

FESA Number

4996

Strain Name

B6.129P2-Grin1<tm2Slab>/H

Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Targeted mutation - Knock out IMSR - congenic strain

Attribution

Institution name Depositor / Originator Name
University College London Originator Retained
University College London Depositor Retained

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Grin1<tm2Slab> MGI:2655237 Grin1 MGI:95819 2

Phenotypic Description

The allele behaves as a Grin1 null allele. Homozygous animals die shortly after birth. Grin1 expression may potentially be induced by tTA or rtTA. Knocked-in tTA DNA segment apparently inactive.

Publications

Displaying 1 - 2 of 2 Stock Publications
Pubmed ID Authors Title Journal
19794189 Chen PE Behavioral deficits and subregion-specific suppression of LTP in mice expressing a population of mutant NMDA receptors throughout the hippocampus. Learn Mem (2 009) 16:635-44
12657691 Rudhard Y Absence of Whisker-related pattern formation in mice with NMDA receptors lacking coincidence detection properties and calcium signaling. J Neurosci (2 003) 23:2323-32

EMMA ID

EM:06320

Genetic Status

GMO

Production Information

Tetracycline-controlled method of mutation

Background Strain Name

C57BL/6J

Background Strain MGI ID

MGI:3028467

Contact/Order

For more information or to order stocks, Contact us