Mutation Strain Type
|Institution name||Depositor / Originator||Name|
|University College London||Originator||Retained|
|University College London||Depositor||Retained|
Heterozygous animals have subregion-specific impairment of hippocampal plasticity, associated with impaired spatial memory and navigation. Homozygeous animals (neo/neo) die shortly after birth. Heterozygous animals with heterozygous global Cre-mediated removal of the neo cassette (Grin1<tm1.1Slab>) die shortly after birth. Therefore the Grin1<tm1.1Slab> allele cannot be maintained.