Stock B6.129P2-Grin1<tm1Slab>/H

FESA Number

4995

Strain Name

B6.129P2-Grin1<tm1Slab>/H

Mutation Strain Type

Attribution

Institution name Depositor / Originator Name
University College London Originator Retained
University College London Depositor Retained

Phenotypic Description

Heterozygous animals have subregion-specific impairment of hippocampal plasticity, associated with impaired spatial memory and navigation. Homozygeous animals (neo/neo) die shortly after birth. Heterozygous animals with heterozygous global Cre-mediated removal of the neo cassette (Grin1<tm1.1Slab>) die shortly after birth. Therefore the Grin1<tm1.1Slab> allele cannot be maintained.

Publications

EMMA ID

EM:06319

Genetic Status

GMO

Background Strain Name

C57BL/6J

Background Strain MGI ID

MGI:3028467

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