Stock B6.129-Prdm1<tm1.1Liz>/RobH

FESA Number

8062

Strain Name

B6.129-Prdm1<tm1.1Liz>/RobH

Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Targeted mutation IMSR - congenic strain

Attribution

Institution name Depositor / Originator Name
University of Oxford Originator Retained
University of Oxford Depositor Retained

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Prdm1<tm1.1Liz> MGI:4366868 Prdm1 MGI:99655 10

Phenotypic Description

No overt phenotype. Mice with targeted exon 1A deletion show that Prdm1 expression has been eliminated in LPS-stimulated B cells and plasma cell differentiation has been blocked. Embryonic development is not disrupted, and embryos with this deletion show modestly reduced Prdm1 expression levels.

Publications

EMMA ID

EM:08438

Genetic Status

GMO

Background Strain Name

C57BL/6J

Background Strain MGI ID

MGI:3028467

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