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Stock B6;129-Gt(ROSA)26Sor<tm1(CAG-Venus/GMNN,Cherry/CDT1)Jkn>/JknH

FESA Number

6899

Strain Name

B6;129-Gt(ROSA)26Sor<tm1(CAG-Venus/GMNN,Cherry/CDT1)Jkn>/JknH

Mutation Strain Type

Attribution

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Gt(ROSA)26Sor<tm1(CAG-Venus/GMNN,-Cherry/CDT1)Jkn> MGI:5645798 Gt(ROSA)26Sor MGI:104735 6

Phenotypic Description

The Fucci system was developed by fusing red- and green-emitting fluorescent proteins to the E3 ligase substrates, Cdt1 and Geminin. These fluorescent probes make it possible to distinguish between cells in the G1 or S/G2/M phases of the cell cycle in live cells/tissue (Sakaue-Sawano al 2008). Fucci2a is a bicistronic version of Fucci2 allowing Cre-mediated tissue-specific expression in mice (Mort, R et al 2014).

Publications

Displaying 71 - 80 of 88 Stock Publications
Pubmed ID Authors Title Journal
23195676 Li L Reduced ENaC activity and blood pressure in mice with genetic knockout of the insulin receptor in the renal collecting duct. Am J Physiol Renal Physiol (2 013) 304:F279-88
22995555 Pennimpede T In vivo knockdown of Brachyury results in skeletal defects and urorectal malformations resembling caudal regression syndrome. Dev Biol (2 012) 372:55-67
22661232 Woo WM Shh maintains dermal papilla identity and hair morphogenesis via a Noggin-Shh regulatory loop. Genes Dev (2 012) 26:1235-46
22253774 Boyer A CTNNB1 signaling in sertoli cells downregulates spermatogonial stem cell activity via WNT4. PLoS One (2 012) 7:e29764
21652647 Häärä O Ectodysplasin and Wnt pathways are required for salivary gland branching morphogenesis. Development (2 011) 138:2681-91
16174759 Li Z Runx1 function in hematopoiesis is required in cells that express Tek. Blood (2 006) 107:106-10
14611632 Rilianawati Spermatogenesis in testes of Dazl null mice after transplantation of wild-type germ cells. Reproduction (2 003) 126:599-604
23132912 Yamamoto Y Targeted gene silencing in mouse germ cells by insertion of a homologous DNA into a piRNA generating locus. Genome Res (2 013) 23:292-9
22846673 Chappuis V Periosteal BMP2 activity drives bone graft healing. Bone (2 012) 51:800-9
15251982 Hadland BK A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development. Blood (2 004) 104:3097-105

Pages

EMMA ID

EM:08395

Genetic Status

GMO

Background Strain Name

C57BL/6

Background Strain MGI ID

MGI:2159769

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