Error message

  • Unable to create CTools CSS cache directory. Check the permissions on your files directory.
  • Unable to create CTools CSS cache directory. Check the permissions on your files directory.

Stock B6;129-Gt(ROSA)26Sor<tm1(CAG-Venus/GMNN,Cherry/CDT1)Jkn>/JknH

FESA Number

6899

Strain Name

B6;129-Gt(ROSA)26Sor<tm1(CAG-Venus/GMNN,Cherry/CDT1)Jkn>/JknH

Mutation Strain Type

Attribution

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Gt(ROSA)26Sor<tm1(CAG-Venus/GMNN,-Cherry/CDT1)Jkn> MGI:5645798 Gt(ROSA)26Sor MGI:104735 6

Phenotypic Description

The Fucci system was developed by fusing red- and green-emitting fluorescent proteins to the E3 ligase substrates, Cdt1 and Geminin. These fluorescent probes make it possible to distinguish between cells in the G1 or S/G2/M phases of the cell cycle in live cells/tissue (Sakaue-Sawano al 2008). Fucci2a is a bicistronic version of Fucci2 allowing Cre-mediated tissue-specific expression in mice (Mort, R et al 2014).

Publications

Displaying 41 - 50 of 88 Stock Publications
Pubmed ID Authors Title Journal
19265661 Tanaka KK Syndecan-4-expressing muscle progenitor cells in the SP engraft as satellite cells during muscle regeneration. Cell Stem Cell (2 009) 4:217-25
20826722 Zhang QS Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol. Blood (2 010) 116:5140-8
25411506 Arruda-Carvalho M Posttraining ablation of adult-generated olfactory granule cells degrades odor-reward memories. J Neurosci (2 014) 34:15793-803
23613711 Dovere L The niche-derived glial cell line-derived neurotrophic factor (GDNF) induces migration of mouse spermatogonial stem/progenitor cells. PLoS One (2 013) 8:e59431
19151727 Kleaveland B Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway. Nat Med (2 009) 15:169-76
21768389 Niu Z MicroRNA-21 regulates the self-renewal of mouse spermatogonial stem cells. Proc Natl Acad Sci U S A (2 011) 108:12740-5
24700869 Tran PV Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models. J Am Soc Nephrol (2 014) 25:2201-12
18316625 Zhang QS Tempol protects against oxidative damage and delays epithelial tumor onset in Fanconi anemia mice. Cancer Res (2 008) 68:1601-8
15947238 Babaev VR Conditional knockout of macrophage PPARgamma increases atherosclerosis in C57BL/6 and low-density lipoprotein receptor-deficient mice. Arterioscler Thromb Vasc Biol (2 005) 25:1647-53
19229314 Duncan AW Ploidy reductions in murine fusion-derived hepatocytes. PLoS Genet (2 009) 5:e1000385

Pages

EMMA ID

EM:08395

Genetic Status

GMO

Background Strain Name

C57BL/6

Background Strain MGI ID

MGI:2159769

Contact/Order

For more information or to order stocks, Contact us