Stock B6;129-Apoe<tm1Bres> Lgals3<tm1Ftl>/CljH
FESA Number
2896
Strain Name
B6;129-Apoe<tm1Bres> Lgals3<tm1Ftl>/CljH
Mutation Strain Type
| Mutation Type | Mutation Subtype | Strain Type |
|---|---|---|
| IMSR - Targeted mutation | IMSR - unclassified |
Attribution
| Institution name | Depositor / Originator | Name |
|---|---|---|
| University of Bristol | Originator | Retained |
| University of Bristol | Depositor | Retained |
Gene/Allele Information
| Allele Name | Allele MGI ID | Gene Name | Gene MGI ID | Chromosome |
|---|---|---|---|---|
| Lgals3<tm1Ftl> | MGI:2386938 | Lgals3 | MGI:96778 | 14 |
| Apoe<tm1Bres> | MGI:2137814 | Apoe | MGI:88057 | 7 |
Phenotypic Description
No overt phenotype reported.
Publications
Displaying 1 - 10 of 156 Stock Publications
| Pubmed ID | Authors | Title | Journal |
|---|---|---|---|
| 25343273 | Baek JH | Galectin-3 activates PPAR? and supports white adipose tissue formation and high-fat diet-induced obesity. | Endocrinology (2 015) 156:147-56 |
| 15361471 | Iacobini C | Galectin-3/AGE-receptor 3 knockout mice show accelerated AGE-induced glomerular injury: evidence for a protective role of galectin-3 as an AGE receptor. | FASEB J (2 004) 18:1773-5 |
| 21573150 | Oliveira FL | Lack of galectin-3 disturbs mesenteric lymph node homeostasis and B cell niches in the course of Schistosoma mansoni infection. | PLoS One (2 011) 6:e19216 |
| 1712312 | Agarwal N | Sequence analysis, expression and chromosomal localization of a gene, isolated from a subtracted human retina cDNA library, that encodes an insulin-like growth factor binding protein (IGFBP2). | Exp Eye Res (1 991) 52:549-61 |
| 9555870 | de Villiers WJ | Macrophage phenotype in mice deficient in both macrophage-colony-stimulating factor (op) and apolipoprotein E. | Arterioscler Thromb Vasc Biol (1 998) 18:631-40 |
| 14614151 | Idel S | A20, a regulator of NFkappaB, maps to an atherosclerosis locus and differs between parental sensitive C57BL/6J and resistant FVB/N strains. | Proc Natl Acad Sci U S A (2 003) 100:14235-40 |
| 12569158 | Lesnik P | Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherogenesis. | J Clin Invest (2 003) 111:333-40 |
| 1423598 | Plump AS | Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. | Cell (1 992) 71:343-53 |
| 11988491 | Silence J | Reduced atherosclerotic plaque but enhanced aneurysm formation in mice with inactivation of the tissue inhibitor of metalloproteinase-1 (TIMP-1) gene. | Circ Res (2 002) 90:897-903 |
| 8962133 | Weng W | Dramatically decreased high density lipoprotein cholesterol, increased remnant clearance, and insulin hypersensitivity in apolipoprotein A-II knockout mice suggest a complex role for apolipoprotein A-II in atherosclerosis susceptibility. | Proc Natl Acad Sci U S A (1 996) 93:14788-94 |
Pages
EMMA ID
EM:02060
Genetic Status
GMO
Background Strain Name
C57BL/6
Background Strain MGI ID
MGI:2159769
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