Stock B6.129-Anpep<tm1Afk>/AfkH

FESA Number

7353

Strain Name

B6.129-Anpep<tm1Afk>/AfkH

Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Targeted mutation - Knock out IMSR - mutant stock

Attribution

Institution name Depositor / Originator Name
Unknown Institution Originator Retained
Unknown Institution Depositor Retained

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Anpep<tm1Afk> MGI:5582781 Anpep MGI:5000466 7

Phenotypic Description

No overt phenotype is seen in mice homozygous for Anpep<tm1aAfk>. However, a delay in mammary development was detected. Similar knock-outs for Anpep have shown a deficiency in tumour vascularisation. This was not assessed for this mutated allele. Heterozygotes had no detectable phenotype. See PMID:22983824.

Publications

Displaying 1 - 1 of 1 Stock Publications
Pubmed ID Authors Title Journal
22983824 Kolb AF Mammary gland development is delayed in mice deficient for aminopeptidase N. Transgenic Res (2 013) 22:425-34

EMMA ID

EM:09063

Genetic Status

GMO

Background Strain Name

C57BL/6

Background Strain MGI ID

MGI:2159769

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