Stock A.129P2-Nat2<tm1Esim>/H

FESA Number


Strain Name


Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Targeted mutation IMSR - unclassified


Institution name Depositor / Originator Name
University of Oxford Originator Retained
University of Oxford Depositor Retained

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Nat2<tm1Esim> MGI:2675637 Nat2 MGI:109201 8

Phenotypic Description

No overt phenotype.


Displaying 1 - 8 of 8 Stock Publications
Pubmed ID Authors Title Journal
12815365 Cornish VA Generation and analysis of mice with a targeted disruption of the arylamine N-acetyltransferase type 2 gene. Pharmacogenomics J (2 003) 3:169-77
18161794 Erickson RP Confirmation of the role of N-acetyltransferase 2 in teratogen-induced cleft palate using transgenics and knockouts. Mol Reprod Dev (2 008) 75:1071-6
17961509 Wakefield L Deletion of a xenobiotic metabolizing gene in mice affects folate metabolism. Biochem Biophys Res Commun (2 007) 364:556-60
17896208 Wakefield L Mouse arylamine N-acetyltransferase 2 (Nat2) expression during embryogenesis: a potential marker for the developing neuroendocrine system. Biomarkers (2 008) 13:106-18
20026257 Wakefield L Characterisation of CpG methylation in the upstream control region of mouse Nat2: evidence for a gene-environment interaction in a polymorphic gene implicated in folate metabolism. Gene (2 010) 452:16-21
15872051 Wakefield L Arylamine N-acetyltransferase 2 expression in the developing heart. J Histochem Cytochem (2 005) 53:583-92
17487534 Wakefield L Ocular defects associated with a null mutation in the mouse arylamine N-acetyltransferase 2 gene. Mamm Genome (2 007) 18:270-6
24205029 Witham KL 5-methyl-tetrahydrofolate and the S-adenosylmethionine cycle in C57BL/6J mouse tissues: gender differences and effects of arylamine N-acetyltransferase-1 deletion. PLoS One (2 013) 8:e77923




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