Stock

FESA Number

2898

Strain Name

129.Cg-Tgm2<tm1Gml> Apoe<tm1Bres>/CljH[cc]

Mutation Strain Type

Attribution

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Apoe<tm1Bres> MGI:2137814 Apoe MGI:88057 7
Tgm2<tm1Gml> MGI:2180638 Tgm2 MGI:98731 2

Phenotypic Description

None.

Publications

Displaying 81 - 90 of 142 Stock Publications
Pubmed ID Authors Title Journal
12810961 Szondy Z Transglutaminase 2-/- mice reveal a phagocytosis-associated crosstalk between macrophages and apoptotic cells. Proc Natl Acad Sci U S A (2 003) 100:7812-7
11592107 Calara F Spontaneous plaque rupture and secondary thrombosis in apolipoprotein E-deficient and LDL receptor-deficient mice. J Pathol (2 001) 195:257-63
7802634 Hayek T Role of HDL apolipoprotein E in cellular cholesterol efflux: studies in apo E knockout transgenic mice. Biochem Biophys Res Commun (1 994) 205:1072-8
21372295 Katsume A Early inflammatory reactions in atherosclerosis are induced by proline-rich tyrosine kinase/reactive oxygen species-mediated release of tumor necrosis factor-alpha and subsequent activation of the p21Cip1/Ets-1/p300 system. Arterioscler Thromb Vasc Biol (2 011) 31:1084-92
8550828 Masucci-Magoulas L Profound induction of hepatic cholesteryl ester transfer protein transgene expression in apolipoprotein E and low density lipoprotein receptor gene knockout mice. A novel mechanism signals changes in plasma cholesterol levels. J Clin Invest (1 996) 97:154-61
11705823 Rong JX Elevating high-density lipoprotein cholesterol in apolipoprotein E-deficient mice remodels advanced atherosclerotic lesions by decreasing macrophage and increasing smooth muscle cell content. Circulation (2 001) 104:2447-52
19416717 Thorp E Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP. Cell Metab (2 009) 9:474-81
10559023 Yang R Hypertension and endothelial dysfunction in apolipoprotein E knockout mice. Arterioscler Thromb Vasc Biol (1 999) 19:2762-8
16691213 Iadevaia V ATP-binding cassette transporter 1 and transglutaminase 2 act on the same genetic pathway in the apoptotic cell clearance. Cell Death Differ (2 006) 13:1998-2001
18594942 Tarantino U FXIIIA and TGF-beta over-expression produces normal musculo-skeletal phenotype in TG2-/- mice. Amino Acids (2 009) 36:679-84

Pages

EMMA ID

EM:02064

Genetic Status

GMO

Background Strain Name

129

Background Strain MGI ID

MGI:2160041

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