Stock

FESA Number

1589

Strain Name

129.Cg-Pax6<Sey> Tg(Hbb-b1)83Clo/WsH

Mutation Strain Type

Attribution

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Pax6<Sey> MGI:1856155 Pax6 MGI:97490 2
Tg(Hbb-b1)83Clo MGI:2655271 3

Phenotypic Description

Reiterated transgene is detectable by DNA in situ hybridisation.

Publications

Displaying 31 - 40 of 141 Stock Publications
Pubmed ID Authors Title Journal
3794606 Hogan BL Small eyes (Sey): a homozygous lethal mutation on chromosome 2 which affects the differentiation of both lens and nasal placodes in the mouse. J Embryol Exp Morphol (1 986) 97:95-110
18507827 Manuel M Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance. BMC Dev Biol (2 008) 8:59
4426343 Pritchard DJ Abnormal lens capsule carbohydrate associated with the dominant gene "small-eye" in the mouse. Exp Eye Res (1 974) 19:335-40
19666824 Smith AN Stage-dependent modes of Pax6-Sox2 epistasis regulate lens development and eye morphogenesis. Development (2 009) 136:2977-85
12764036 Tyas DA Pax6 regulates cell adhesion during cortical development. Cereb Cortex (2 003) 13:612-9
8290590 Ioffe E Mice lacking N-acetylglucosaminyltransferase I activity die at mid-gestation, revealing an essential role for complex or hybrid N-linked carbohydrates. Proc Natl Acad Sci U S A (1 994) 91:728-32
17064680 Blixt A Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage. Dev Biol (2 007) 302:218-29
17942732 Costa MR The marginal zone/layer I as a novel niche for neurogenesis and gliogenesis in developing cerebral cortex. J Neurosci (2 007) 27:11376-88
19258013 Genethliou N Spatially distinct functions of PAX6 and NKX2.2 during gliogenesis in the ventral spinal cord. Biochem Biophys Res Commun (2 009) 382:69-73
Hogan BL Allelism of small eyes (Sey) with Dickie's small eye (Dey) on Chromosome 2. Mouse News Lett (1 987) 77:135-8

Pages

Orphanet Categories

Rare developmental defect during embryogenesis
Rare urogenital disease
Rare renal disease
Rare eye disease
Rare endocrine disease
Rare oncologic disease
Rare gynecologic or obstetric disease
Rare neurologic disease

EMMA ID

EM:01891

Contact/Order

For more information or to order stocks, Contact us