Stock 129.Cg-Pax6<Sey> Tg(Hbb-b1)83Clo/WsH

FESA Number


Strain Name

129.Cg-Pax6<Sey> Tg(Hbb-b1)83Clo/WsH

Mutation Strain Type


Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Pax6<Sey> MGI:1856155 Pax6 MGI:97490 2
Tg(Hbb-b1)83Clo MGI:2655271 3

Phenotypic Description

Reiterated transgene is detectable by DNA in situ hybridisation.


Displaying 31 - 40 of 141 Stock Publications
Pubmed ID Authors Title Journal
3794606 Hogan BL Small eyes (Sey): a homozygous lethal mutation on chromosome 2 which affects the differentiation of both lens and nasal placodes in the mouse. J Embryol Exp Morphol (1 986) 97:95-110
18507827 Manuel M Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance. BMC Dev Biol (2 008) 8:59
4426343 Pritchard DJ Abnormal lens capsule carbohydrate associated with the dominant gene "small-eye" in the mouse. Exp Eye Res (1 974) 19:335-40
19666824 Smith AN Stage-dependent modes of Pax6-Sox2 epistasis regulate lens development and eye morphogenesis. Development (2 009) 136:2977-85
12764036 Tyas DA Pax6 regulates cell adhesion during cortical development. Cereb Cortex (2 003) 13:612-9
8290590 Ioffe E Mice lacking N-acetylglucosaminyltransferase I activity die at mid-gestation, revealing an essential role for complex or hybrid N-linked carbohydrates. Proc Natl Acad Sci U S A (1 994) 91:728-32
17064680 Blixt A Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage. Dev Biol (2 007) 302:218-29
17942732 Costa MR The marginal zone/layer I as a novel niche for neurogenesis and gliogenesis in developing cerebral cortex. J Neurosci (2 007) 27:11376-88
19258013 Genethliou N Spatially distinct functions of PAX6 and NKX2.2 during gliogenesis in the ventral spinal cord. Biochem Biophys Res Commun (2 009) 382:69-73
Hogan BL Allelism of small eyes (Sey) with Dickie's small eye (Dey) on Chromosome 2. Mouse News Lett (1 987) 77:135-8


Orphanet Categories

Rare developmental defect during embryogenesis
Rare urogenital disease
Rare renal disease
Rare eye disease
Rare endocrine disease
Rare oncologic disease
Rare gynecologic or obstetric disease
Rare neurologic disease




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