Stock 129(B6)-Apoe<tm1Bres> Plat<tm1Mlg>/CljH[cc]

FESA Number


Strain Name

129(B6)-Apoe<tm1Bres> Plat<tm1Mlg>/CljH[cc]

Mutation Strain Type


Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Apoe<tm1Bres> MGI:2137814 Apoe MGI:88057 7
Plat<tm1Mlg> MGI:1857288 Plat MGI:97610 8

Phenotypic Description



Displaying 221 - 230 of 240 Stock Publications
Pubmed ID Authors Title Journal
16125860 Matys T Tissue plasminogen activator in the bed nucleus of stria terminalis regulates acoustic startle. Neuroscience (2 005) 135:715-22
15486301 Pang PT Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity. Science (2 004) 306:487-91
10216203 Ripley TL Increased sensitivity to cocaine, and over-responding during cocaine self-administration in tPA knockout mice. Brain Res (1 999) 826:117-27
8987777 Tsirka SE An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus. J Neurosci (1 997) 17:543-52
14630814 Zhao BQ Essential role of endogenous tissue plasminogen activator through matrix metalloproteinase 9 induction and expression on heparin-produced cerebral hemorrhage after cerebral ischemia in mice. Blood (2 004) 103:2610-6
10393696 Dansky HM Apo A-I inhibits foam cell formation in Apo E-deficient mice after monocyte adherence to endothelium. J Clin Invest (1 999) 104:31-9
11551841 Hirano T Apoprotein C-III deficiency markedly stimulates triglyceride secretion in vivo: comparison with apoprotein E. Am J Physiol Endocrinol Metab (2 001) 281:E665-9
15625075 Lassila M Imatinib attenuates diabetic nephropathy in apolipoprotein E-knockout mice. J Am Soc Nephrol (2 005) 16:363-73
7511933 Palinski W ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum. Arterioscler Thromb (1 994) 14:605-16
19359600 She ZG Human paraoxonase gene cluster transgenic overexpression represses atherogenesis and promotes atherosclerotic plaque stability in ApoE-null mice. Circ Res (2 009) 104:1160-8




Genetic Status


Background Strain Name


Background Strain MGI ID



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