Imprinting LociChromosomeChromosomal RegionExpressed parental allele: maternal (M)/ paternal (P)Name
Peg10 6prox 6Ppaternally expressed 10
Gene Synonyms
Edr,HB-1,Mar2,MEF3L,Mart2,MyEF-3,MyEF-3 like
Gene References
Monk D,Wagschal A,Arnaud P,Müller PS,Parker-Katiraee L,Bourc'his D,Scherer SW,Feil R,Stanier P,Moore GE Comparative analysis of human chromosome 7q21 and mouse proximal chromosome 6 reveals a placental-specific imprinted gene, TFPI2/Tfpi2, which requires EHMT2 and EED for allelic-silencing. Genome research. 2008();18(8):1270-81 PUBMED
Clark MB,Jänicke M,Gottesbühren U,Kleffmann T,Legge M,Poole ES,Tate WP Mammalian gene PEG10 expresses two reading frames by high efficiency -1 frameshifting in embryonic-associated tissues. The Journal of biological chemistry. 2007();282(52):37359-69 PUBMED
Hishida T,Naito K,Osada S,Nishizuka M,Imagawa M peg10, an imprinted gene, plays a crucial role in adipocyte differentiation. FEBS letters. 2007();581(22):4272-8 PUBMED
Frankenberg S,Smith L,Greenfield A,Zernicka-Goetz M Novel gene expression patterns along the proximo-distal axis of the mouse embryo before gastrulation. BMC developmental biology. 2007();7():8 PUBMED
Kamei Y,Suganami T,Kohda T,Ishino F,Yasuda K,Miura S,Ezaki O,Ogawa Y Peg1/Mest in obese adipose tissue is expressed from the paternal allele in an isoform-specific manner. FEBS letters. 2007();581(1):91-6 PUBMED
Ogawa H,Wu Q,Komiyama J,Obata Y,Kono T Disruption of parental-specific expression of imprinted genes in uniparental fetuses. FEBS letters. 2006();580(22):5377-84 PUBMED
Ono R,Nakamura K,Inoue K,Naruse M,Usami T,Wakisaka-Saito N,Hino T,Suzuki-Migishima R,Ogonuki N,Miki H,Kohda T,Ogura A,Yokoyama M,Kaneko-Ishino T,Ishino F Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality. Nature genetics. 2006();38(1):101-6 PUBMED
Brandt J,Veith AM,Volff JN A family of neofunctionalized Ty3/gypsy retrotransposon genes in mammalian genomes. Cytogenetic and genome research. 2005();110(1-4):307-17 PUBMED
McKee AE,Minet E,Stern C,Riahi S,Stiles CD,Silver PA A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC developmental biology. 2005();5():14 PUBMED
Show 8 more Gene References below
Uniparental DuplicationProxBkptDisBkptEffects
MatDp(prox6) centromere to A3.2centT77Hearly embryonic lethality
Region References
Beechey CV A reassessment of imprinting regions and phenotypes on mouse chromosome 6: Nap1l5 locates within the currently defined sub-proximal imprinting region. Cytogenetic and genome research. 2004();107(1-2):108-14 PUBMED
Beechey CV Peg1/Mest locates distal to the currently defined imprinting region on mouse proximal chromosome 6 and identifies a new imprinting region affecting growth. Cytogenetics and cell genetics. 2000();90(3-4):309-14 PUBMED
Allele SymbolAllele NameMGI IDENSEMBLREFSEQ
Peg10<tm1Fuis>targeted mutation 1, Fumitoshi IshinoMGI:3620548ENSEMBLNM_001040611