Stock STOCK Epo<Tg(SV40T/Epo)134.3LCPjr>/H
FESA Number
1146
Strain Name
STOCK Epo<Tg(SV40T/Epo)134.3LCPjr>/H
Mutation Strain Type
| Mutation Type | Mutation Subtype | Strain Type |
|---|---|---|
| IMSR - Transgenic | IMSR - mutant stock |
Attribution
| Institution name | Depositor / Originator | Name |
|---|---|---|
| Unknown Institution | Originator | Retained |
| Unknown Institution | Depositor | Retained |
Gene/Allele Information
| Allele Name | Allele MGI ID | Gene Name | Gene MGI ID | Chromosome |
|---|---|---|---|---|
| Epo<Tg(SV40T/Epo)134.3LCPjr> | MGI:3767166 | 5 |
Phenotypic Description
Homozygotes have incomplete epo deficiency and are anaemic.
Publications
Displaying 1 - 9 of 9 Stock Publications
| Pubmed ID | Authors | Title | Journal |
|---|---|---|---|
| 18188450 | Angelillo-Scherrer A | Role of Gas6 in erythropoiesis and anemia in mice. | J Clin Invest (2 008) 118:583-96 |
| 12239150 | Binley K | Long-term reversal of chronic anemia using a hypoxia-regulated erythropoietin gene therapy. | Blood (2 002) 100:2406-13 |
| 16445835 | Du Roure C | Correction of severe anaemia using immuno-regulated gene therapy is achieved by restoring the early erythroblast compartment. | Br J Haematol (2 006) 132:608-14 |
| 19109375 | El Hasnaoui-Saadani R | Cerebral adaptations to chronic anemia in a model of erythropoietin-deficient mice exposed to hypoxia. | Am J Physiol Regul Integr Comp Physiol (2 009) 296:R801-11 |
| 21816364 | Hoch M | Erythropoietin preserves the endothelial differentiation capacity of cardiac progenitor cells and reduces heart failure during anticancer therapies. | Cell Stem Cell (2 011) 9:131-43 |
| 16330260 | Macarlupú JL | Time course of ventilatory acclimatisation to hypoxia in a model of anemic transgenic mice. | Respir Physiol Neurobiol (2 006) 153:14-22 |
| 15878311 | Macarlupú JL | Characterisation of the ventilatory response to hypoxia in a model of transgenic anemic mice. | Respir Physiol Neurobiol (2 006) 150:19-26 |
| 8264149 | Maxwell PH | Identification of the renal erythropoietin-producing cells using transgenic mice. | Kidney Int (1 993) 44:1149-62 |
| 22342523 | Mowat FM | Endogenous erythropoietin protects neuroretinal function in ischemic retinopathy. | Am J Pathol (2 012) 180:1726-39 |
EMMA ID
EM:02595
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