Stock

FESA Number

7180

Strain Name

STOCK bicm2

Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Targeted mutation IMSR - mutant stock

Attribution

Institution name Depositor / Originator Name
Unknown Institution Originator Retained
Unknown Institution Depositor Retained

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Mir155<tm1.1Brd> MGI:3709881 Mir155 MGI:2676840 16

Phenotypic Description

No overt phenotype reported.

Publications

Displaying 1 - 10 of 17 Stock Publications
Pubmed ID Authors Title Journal
24270517 Agudo J The miR-126-VEGFR2 axis controls the innate response to pathogen-associated nucleic acids. Nat Immunol (2 014) 15:54-62
18055230 Vigorito E microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells. Immunity (2 007) 27:847-59
23264052 Clare S Enhanced susceptibility to Citrobacter rodentium infection in microRNA-155-deficient mice. Infect Immun (2 013) 81:723-32
25995365 Curtis AM Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1. Proc Natl Acad Sci U S A (2 015) 112:7231-6
21385848 Dunand-Sauthier I Silencing of c-Fos expression by microRNA-155 is critical for dendritic cell maturation and function. Blood (2 011) 117:4490-500
23956210 Heymans S Macrophage microRNA-155 promotes cardiac hypertrophy and failure. Circulation (2 013) 128:1420-32
23200854 Huffaker TB Epistasis between microRNAs 155 and 146a during T cell-mediated antitumor immunity. Cell Rep (2 012) 2:1697-709
25367574 Hu R miR-155 promotes T follicular helper cell accumulation during chronic, low-grade inflammation. Immunity (2 014) 41:605-19
23686497 Hu R MicroRNA-155 confers encephalogenic potential to Th17 cells by promoting effector gene expression. J Immunol (2 013) 190:5972-80
22113163 Kasinski AL Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy. Nat Rev Cancer (2 011) 11:849-64

Pages

EMMA ID

EM:08679

Genetic Status

GMO

Background Strain Name

C57BL/6

Background Strain MGI ID

MGI:2159769

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