Stock B6.Cg-Tyr<c-Brd> Mir155<tm1.1Brd>/H

FESA Number

1885

Strain Name

B6.Cg-Tyr<c-Brd> Mir155<tm1.1Brd>/H

Mutation Strain Type

Attribution

Institution name Depositor / Originator Name
Welcome Trust Sanger Institute Originator Retained
Welcome Trust Sanger Institute Depositor Retained

Phenotypic Description

No visible phenotype is associated with this mutation but the mice do exhibit reduced lung airway remodelling & deficient B-cell, T-cell & dendritic cell function. This mutation is on a C57BL/6<c-/c-> background and is albino in appearance. The BIC mice (EMMA ID EM:02231) have been backcrossed at least 5 times to C57BL/6, thus making them suitable for bone marrow transplantation, without rejection, to any C57BL/6 mice, regardless of coat color.

Orphanet Disorders

OrphaNet ID Name Url
352 734 Minimal pigment oculocutaneous albinism type 1 http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=352734
352 737 Temperature-sensitive oculocutaneous albinism type 1 http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=352737
352 740 Ocular albinism with congenital sensorineural deafness http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=352740
79 434 Oculocutaneous albinism type 1B http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=79434
79 431 Oculocutaneous albinism type 1A http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=79431

Publications

Orphanet Categories

Inborn errors of metabolism
Rare skin disease
Rare eye disease

EMMA ID

EM:02231

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