Stock B6.Cg-Tyr<c-Brd> Mir155<tm1.1Brd>/H

FESA Number


Strain Name

B6.Cg-Tyr<c-Brd> Mir155<tm1.1Brd>/H

Mutation Strain Type


Institution name Depositor / Originator Name
Welcome Trust Sanger Institute Originator Retained
Welcome Trust Sanger Institute Depositor Retained

Phenotypic Description

No visible phenotype is associated with this mutation but the mice do exhibit reduced lung airway remodelling & deficient B-cell, T-cell & dendritic cell function. This mutation is on a C57BL/6<c-/c-> background and is albino in appearance. The BIC mice (EMMA ID EM:02231) have been backcrossed at least 5 times to C57BL/6, thus making them suitable for bone marrow transplantation, without rejection, to any C57BL/6 mice, regardless of coat color.

Orphanet Disorders

OrphaNet ID Name Url
352 734 Minimal pigment oculocutaneous albinism type 1
352 737 Temperature-sensitive oculocutaneous albinism type 1
352 740 Ocular albinism with congenital sensorineural deafness
79 434 Oculocutaneous albinism type 1B
79 431 Oculocutaneous albinism type 1A


Orphanet Categories

Inborn errors of metabolism
Rare skin disease
Rare eye disease




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