Stock B6.Cg-Syce1<tm1Hgu>/H

FESA Number

3553

Strain Name

B6.Cg-Syce1<tm1Hgu>/H

Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Targeted mutation IMSR - mutant strain

Attribution

Institution name Depositor / Originator Name
MRC Human Genetics Unit Originator Retained
MRC Human Genetics Unit Depositor Retained

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Syce1<tm1Hgu> MGI:3840564 Syce1 MGI:1921325 7

Phenotypic Description

Mice homozygous for this mutation in this background can not progress to diplotene stages of meiosis and show a failure of synapsis. Heterozygous mice show close to normal fertility.

Publications

Displaying 1 - 1 of 1 Stock Publications
Pubmed ID Authors Title Journal
19247432 Bolcun-Filas E Mutation of the mouse Syce1 gene disrupts synapsis and suggests a link between synaptonemal complex structural components and DNA repair. PLoS Genet (2 009) 5:e1000393

EMMA ID

EM:04538

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