Stock B6.129S-Otoa<tm1Gpr>/H

FESA Number

4850

Strain Name

B6.129S-Otoa<tm1Gpr>/H

Mutation Strain Type

Attribution

Institution name Depositor / Originator Name
Unknown Institution Originator Retained
Unknown Institution Depositor Retained

Severity Limit

Mild

Phenotypic Description

In null mutant (OtoaEGFP/EGFP) mice the TM is detached at the spiral limbus but remains attached to the outer hair cells, Hensen's stripe is missing and the marginal band appears abnormal. Null mutants show hearing loss but excitation of the outer hair cells and cochlear amplification are almost normal.

Publications

EMMA ID

EM:05545

Genetic Status

GMO

Background Strain Name

C57BL/6J

Background Strain MGI ID

MGI:3028467

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