Stock B6;129P2-Slc7a10<tm1Dgen>/H

FESA Number

1923

Strain Name

B6;129P2-Slc7a10<tm1Dgen>/H

Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Targeted mutation IMSR - mutant stock

Attribution

Institution name Depositor / Originator Name
Deltagen Originator Retained
Deltagen Depositor Retained

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Slc7a10<tm1Dgen> MGI:3716074 Slc7a10 MGI:1858261 7

Phenotypic Description

No visible phenotype.

Publications

Displaying 1 - 3 of 3 Stock Publications
Pubmed ID Authors Title Journal
17432963 Rutter AR Evidence from gene knockout studies implicates Asc-1 as the primary transporter mediating d-serine reuptake in the mouse CNS. Eur J Neurosci (2 007) 25:1757-66
25755256 Safory H The alanine-serine-cysteine-1 (Asc-1) transporter controls glycine levels in the brain and is required for glycinergic inhibitory transmission. EMBO Rep (2 015) 16:590-8
16026768 Xie X Lack of the alanine-serine-cysteine transporter 1 causes tremors, seizures, and early postnatal death in mice. Brain Res (2 005) 1052:212-21

EMMA ID

EM:02361

Genetic Status

GMO

Background Strain Name

C57BL/6J

Background Strain MGI ID

MGI:3028467

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