Stock B6;129P2-P2rx6<tm1Dgen>/H
FESA Number
1922
Strain Name
B6;129P2-P2rx6<tm1Dgen>/H
Mutation Strain Type
| Mutation Type | Mutation Subtype | Strain Type |
|---|---|---|
| IMSR - Targeted mutation | IMSR - mutant stock |
Attribution
| Institution name | Depositor / Originator | Name |
|---|---|---|
| Deltagen | Originator | Retained |
| Deltagen | Depositor | Retained |
Gene/Allele Information
| Allele Name | Allele MGI ID | Gene Name | Gene MGI ID | Chromosome |
|---|---|---|---|---|
| P2rx6<tm1Dgen> | MGI:5427682 | P2rx6 | MGI:1337113 | 16 |
Phenotypic Description
Homozygous mutant mice exhibited a significant increase in thermal response latency
during hot plate testing, and required a significantly increased dose of metrazol to reach various
seizure stages, when compared with age- and gender-matched wild-type control mice. There
were no other significant differences detected in homozygous mutant mice when compared with
age- and gender-matched wild-type control mice.
Publications
Displaying 1 - 1 of 1 Stock Publications
| Pubmed ID | Authors | Title | Journal |
|---|---|---|---|
| European Mouse Mutant Archive | Information obtained from the European Mouse Mutant Archive (EMMA) | Unpublished (2 003) : |
EMMA ID
EM:02371
Genetic Status
GMO
Background Strain Name
C57BL/6J
Background Strain MGI ID
MGI:3028467
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