Stock

FESA Number

1908

Strain Name

B6;129P2-Grm1<tm1Dgen>/H

Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Targeted mutation IMSR - mutant stock

Attribution

Institution name Depositor / Originator Name
Deltagen Originator Retained
Deltagen Depositor Retained

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Grm1<tm1Dgen> MGI:3604591 Grm1 MGI:1351338 10

Phenotypic Description

No visible phenotype.

Orphanet Disorders

OrphaNet ID Name Url
324 262 Autosomal recessive congenital cerebellar ataxia due to MGLUR1 deficiency http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=324262

Publications

Displaying 1 - 3 of 3 Stock Publications
Pubmed ID Authors Title Journal
Deltagen Inc NIH initiative supporting placement of Deltagen, Inc. mice into public repositories MGI Direct Data Submission (2 005) :
23115168 Kato AS Glutamate receptor ?2 associates with metabotropic glutamate receptor 1 (mGluR1), protein kinase C?, and canonical transient receptor potential 3 and regulates mGluR1-mediated synaptic transmission in cerebellar Purkinje neurons. J Neurosci (2 012) 32:15296-308
17934773 Sachs AJ The mouse mutants recoil wobbler and nmf373 represent a series of Grm1 mutations. Mamm Genome (2 007) 18:749-56

Orphanet Categories

Inborn errors of metabolism
Rare neurologic disease

EMMA ID

EM:02357

Background Strain Name

C57BL/6J

Background Strain MGI ID

MGI:3028467

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