Stock B6.129P2-Efnb1<tm1Rha>/Rha

FESA Number

4350

Strain Name

B6.129P2-Efnb1<tm1Rha>/Rha

Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Targeted mutation IMSR - unclassified

Attribution

Institution name Depositor / Originator Name
University of Oxford Originator Retained
University of Oxford Depositor Retained

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Efnb1<tm1Rha> MGI:3653699 Efnb1 MGI:102708 X

Phenotypic Description

Knockout mice exhibit omphalocele, mispaired sternabrae, palate abnormalities, skull abnormalities, females additionally exhibit polysyndactyly.

Orphanet Disorders

OrphaNet ID Name Url
1 520 Craniofrontonasal dysplasia http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=1520

Publications

Displaying 1 - 2 of 2 Stock Publications
Pubmed ID Authors Title Journal
12919674 Compagni A Control of skeletal patterning by ephrinB1-EphB interactions. Dev Cell (2 003) 5:217-30
21460838 Sentürk A Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration. Nature (2 011) 472:356-60

Orphanet Categories

Rare developmental defect during embryogenesis
Rare neurologic disease
Rare bone disease

EMMA ID

EM:05101

Genetic Status

GMO

Contact/Order

For more information or to order stocks, Contact us