Stock B6;129-Scn10a<tm3(cre/ERT2)Jnw>/H

FESA Number

3448

Strain Name

B6;129-Scn10a<tm3(cre/ERT2)Jnw>/H

Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Targeted mutation IMSR - unclassified

Attribution

Institution name Depositor / Originator Name
University College London Originator Retained
University College London Depositor Retained

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Scn10a<tm3(cre/ERT2)Jnw> MGI:3689893 Scn10a MGI:108029 9

Phenotypic Description

None observed (heterozygous Nav1.8-CreERT2 can express enough Cre to delete the floxed fragment, but it does not affect the expression of Nav1.8 in Nav1.8 positive neurons in DRG).

Publications

Displaying 1 - 1 of 1 Stock Publications
Pubmed ID Authors Title Journal
16850455 Zhao J Tamoxifen-inducible NaV1.8-CreERT2 recombinase activity in nociceptive neurons of dorsal root ganglia. Genesis (2 006) 44:364-71

EMMA ID

EM:02603

Genetic Status

GMO

Production Information

Cre-Lox Recombination based excision

Background Strain Name

C57BL/6

Background Strain MGI ID

MGI:2159769

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