Stock B6;129-Reg2<tm1Lchr>/H
FESA Number
3427
Strain Name
B6;129-Reg2<tm1Lchr>/H
Mutation Strain Type
| Mutation Type | Mutation Subtype | Strain Type |
|---|---|---|
| IMSR - Targeted mutation | IMSR - unclassified |
Attribution
| Institution name | Depositor / Originator | Name |
|---|---|---|
| University College London | Originator | Retained |
| University College London | Depositor | Retained |
Gene/Allele Information
| Allele Name | Allele MGI ID | Gene Name | Gene MGI ID | Chromosome |
|---|---|---|---|---|
| Reg2<tm1Lchr> | MGI:3812476 | Reg2 | MGI:97896 | 6 |
Phenotypic Description
Viable, normal breeding pattern, no obvious phenotype.
Publications
Displaying 1 - 4 of 4 Stock Publications
| Pubmed ID | Authors | Title | Journal |
|---|---|---|---|
| 23867474 | Gironella M | Reg3? deficiency impairs pancreatic tumor growth by skewing macrophage polarization. | Cancer Res (2 013) 73:5682-94 |
| 17133485 | Lieu HT | Reg2 inactivation increases sensitivity to Fas hepatotoxicity and delays liver regeneration post-hepatectomy in mice. | Hepatology (2 006) 44:1452-64 |
| 18678917 | Tebar LA | Deletion of the mouse RegIIIbeta (Reg2) gene disrupts ciliary neurotrophic factor signaling and delays myelination of mouse cranial motor neurons. | Proc Natl Acad Sci U S A (2 008) 105:11400-5 |
| 22252863 | van Ampting MT | Intestinally secreted C-type lectin Reg3b attenuates salmonellosis but not listeriosis in mice. | Infect Immun (2 012) 80:1115-20 |
EMMA ID
EM:03572
Genetic Status
GMO
Background Strain Name
C57BL/6
Background Strain MGI ID
MGI:2159769
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