Stock B6;129-Reg2<tm1Lchr>/H

FESA Number

3427

Strain Name

B6;129-Reg2<tm1Lchr>/H

Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Targeted mutation IMSR - unclassified

Attribution

Institution name Depositor / Originator Name
University College London Originator Retained
University College London Depositor Retained

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Reg2<tm1Lchr> MGI:3812476 Reg2 MGI:97896 6

Phenotypic Description

Viable, normal breeding pattern, no obvious phenotype.

Publications

Displaying 1 - 4 of 4 Stock Publications
Pubmed ID Authors Title Journal
23867474 Gironella M Reg3? deficiency impairs pancreatic tumor growth by skewing macrophage polarization. Cancer Res (2 013) 73:5682-94
17133485 Lieu HT Reg2 inactivation increases sensitivity to Fas hepatotoxicity and delays liver regeneration post-hepatectomy in mice. Hepatology (2 006) 44:1452-64
18678917 Tebar LA Deletion of the mouse RegIIIbeta (Reg2) gene disrupts ciliary neurotrophic factor signaling and delays myelination of mouse cranial motor neurons. Proc Natl Acad Sci U S A (2 008) 105:11400-5
22252863 van Ampting MT Intestinally secreted C-type lectin Reg3b attenuates salmonellosis but not listeriosis in mice. Infect Immun (2 012) 80:1115-20

EMMA ID

EM:03572

Genetic Status

GMO

Background Strain Name

C57BL/6

Background Strain MGI ID

MGI:2159769

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