Stock B6.129-Prdm1<tm1.1Liz>/RobH

FESA Number

8707

Strain Name

B6.129-Prdm1<tm1.1Liz>/RobH

Mutation Strain Type

Attribution

Institution name Depositor / Originator Name
University of Oxford Originator Retained
University of Oxford Depositor Retained

Phenotypic Description

No overt phenotype. Mice with targeted exon 1A deletion show that Prdm1 expression has been eliminated in LPS-stimulated B cells and plasma cell differentiation has been blocked. Embryonic development is not disrupted, and embryos with this deletion show modestly reduced Prdm1 expression levels.

Publications

EMMA ID

EM:08438

Genetic Status

GMO

Background Strain Name

C57BL/6J

Background Strain MGI ID

MGI:3028467

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