Mutation Strain Type
|Institution name||Depositor / Originator||Name|
|University of Oxford||Originator||Retained|
|University of Oxford||Depositor||Retained|
No overt phenotype. Mice with targeted exon 1A deletion show that Prdm1 expression has been eliminated in LPS-stimulated B cells and plasma cell differentiation has been blocked. Embryonic development is not disrupted, and embryos with this deletion show modestly reduced Prdm1 expression levels.