Stock B6;129-Gt(ROSA)26Sor<tm1(CAG-Venus/GMNN,Cherry/CDT1)Jkn>/JknH

FESA Number

6899

Strain Name

B6;129-Gt(ROSA)26Sor<tm1(CAG-Venus/GMNN,Cherry/CDT1)Jkn>/JknH

Mutation Strain Type

Attribution

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Gt(ROSA)26Sor<tm1(CAG-Venus/GMNN,-Cherry/CDT1)Jkn> MGI:5645798 Gt(ROSA)26Sor MGI:104735 6

Phenotypic Description

The Fucci system was developed by fusing red- and green-emitting fluorescent proteins to the E3 ligase substrates, Cdt1 and Geminin. These fluorescent probes make it possible to distinguish between cells in the G1 or S/G2/M phases of the cell cycle in live cells/tissue (Sakaue-Sawano al 2008). Fucci2a is a bicistronic version of Fucci2 allowing Cre-mediated tissue-specific expression in mice (Mort, R et al 2014).

Publications

Displaying 81 - 88 of 88 Stock Publications
Pubmed ID Authors Title Journal
18957687 Lugus JJ Both primitive and definitive blood cells are derived from Flk-1+ mesoderm. Blood (2 009) 113:563-6
9640329 Robinson ML Disregulation of ocular morphogenesis by lens-specific expression of FGF-3/int-2 in transgenic mice. Dev Biol (1 998) 198:13-31
23221369 Yang QE MicroRNAs 221 and 222 regulate the undifferentiated state in mammalian male germ cells. Development (2 013) 140:280-90
16675530 Chi L Sprouty2 is involved in male sex organogenesis by controlling fibroblast growth factor 9-induced mesonephric cell migration to the developing testis. Endocrinology (2 006) 147:3777-88
20956382 Hirai H MyoD regulates apoptosis of myoblasts through microRNA-mediated down-regulation of Pax3. J Cell Biol (2 010) 191:347-65
16207763 Matt N Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells. Development (2 005) 132:4789-800
17377529 Samokhvalov IM Cell tracing shows the contribution of the yolk sac to adult haematopoiesis. Nature (2 007) 446:1056-61
23239029 Yang QE CXCL12-CXCR4 signaling is required for the maintenance of mouse spermatogonial stem cells. J Cell Sci (2 013) 126:1009-20

Pages

EMMA ID

EM:08395

Genetic Status

GMO

Background Strain Name

C57BL/6

Background Strain MGI ID

MGI:2159769

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