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Stock B6;129-Gt(ROSA)26Sor<tm1(CAG-Venus/GMNN,Cherry/CDT1)Jkn>/JknH

FESA Number

6899

Strain Name

B6;129-Gt(ROSA)26Sor<tm1(CAG-Venus/GMNN,Cherry/CDT1)Jkn>/JknH

Mutation Strain Type

Attribution

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Gt(ROSA)26Sor<tm1(CAG-Venus/GMNN,-Cherry/CDT1)Jkn> MGI:5645798 Gt(ROSA)26Sor MGI:104735 6

Phenotypic Description

The Fucci system was developed by fusing red- and green-emitting fluorescent proteins to the E3 ligase substrates, Cdt1 and Geminin. These fluorescent probes make it possible to distinguish between cells in the G1 or S/G2/M phases of the cell cycle in live cells/tissue (Sakaue-Sawano al 2008). Fucci2a is a bicistronic version of Fucci2 allowing Cre-mediated tissue-specific expression in mice (Mort, R et al 2014).

Publications

Displaying 51 - 60 of 88 Stock Publications
Pubmed ID Authors Title Journal
18682239 Kobayashi A Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development. Cell Stem Cell (2 008) 3:169-81
21543770 Oatley MJ Inhibitor of DNA binding 4 is expressed selectively by single spermatogonia in the male germline and regulates the self-renewal of spermatogonial stem cells in mice. Biol Reprod (2 011) 85:347-56
22076439 Veikkolainen V ErbB4 modulates tubular cell polarity and lumen diameter during kidney development. J Am Soc Nephrol (2 012) 23:112-22
18182616 Baba M Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys. J Natl Cancer Inst (2 008) 100:140-54
22368271 Follenzi A Role of bone marrow transplantation for correcting hemophilia A in mice. Blood (2 012) 119:5532-42
11130972 Kohlhepp RL ROSA26 mice carry a modifier of Min-induced mammary and intestinal tumor development. Mamm Genome (2 000) 11:1058-62
17210634 Parisi T Selective requirements for E2f3 in the development and tumorigenicity of Rb-deficient chimeric tissues. Mol Cell Biol (2 007) 27:2283-93
20876523 Verma M Efficient single muscle fiber isolation from alcohol-fixed adult muscle following ?-galactosidase staining for satellite cell detection. J Histochem Cytochem (2 011) 59:60-7
22685206 Babar IA Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma. Proc Natl Acad Sci U S A (2 012) 109:E1695-704
15472070 Fraidenraich D Rescue of cardiac defects in id knockout embryos by injection of embryonic stem cells. Science (2 004) 306:247-52

Pages

EMMA ID

EM:08395

Genetic Status

GMO

Background Strain Name

C57BL/6

Background Strain MGI ID

MGI:2159769

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