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Stock B6;129-Gt(ROSA)26Sor<tm1(CAG-Venus/GMNN,Cherry/CDT1)Jkn>/JknH

FESA Number

6899

Strain Name

B6;129-Gt(ROSA)26Sor<tm1(CAG-Venus/GMNN,Cherry/CDT1)Jkn>/JknH

Mutation Strain Type

Attribution

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Gt(ROSA)26Sor<tm1(CAG-Venus/GMNN,-Cherry/CDT1)Jkn> MGI:5645798 Gt(ROSA)26Sor MGI:104735 6

Phenotypic Description

The Fucci system was developed by fusing red- and green-emitting fluorescent proteins to the E3 ligase substrates, Cdt1 and Geminin. These fluorescent probes make it possible to distinguish between cells in the G1 or S/G2/M phases of the cell cycle in live cells/tissue (Sakaue-Sawano al 2008). Fucci2a is a bicistronic version of Fucci2 allowing Cre-mediated tissue-specific expression in mice (Mort, R et al 2014).

Publications

Displaying 31 - 40 of 88 Stock Publications
Pubmed ID Authors Title Journal
18171685 Arnold SJ Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse. Development (2 008) 135:501-11
21557454 Cuttler AS Characterization of Pdgfrb-Cre transgenic mice reveals reduction of ROSA26 reporter activity in remodeling arteries. Genesis (2 011) 49:673-80
15048812 Jäger R Cell type-specific conditional regulation of the c-myc proto-oncogene by combining Cre/loxP recombination and tamoxifen-mediated activation. Genesis (2 004) 38:145-50
10934257 Nguyen QT Nerve terminals form but fail to mature when postsynaptic differentiation is blocked: in vivo analysis using mammalian nerve-muscle chimeras. J Neurosci (2 000) 20:6077-86
15677726 Takahashi Y Differential contributions of Mesp1 and Mesp2 to the epithelialization and rostro-caudal patterning of somites. Development (2 005) 132:787-96
24892805 Zhang H NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-?B. J Clin Invest (2 014) 124:3200-14
22016545 Arruda-Carvalho M Posttraining ablation of adult-generated neurons degrades previously acquired memories. J Neurosci (2 011) 31:15113-27
22729177 Dietrich MO AgRP neurons regulate development of dopamine neuronal plasticity and nonfood-associated behaviors. Nat Neurosci (2 012) 15:1108-10
10887078 Kitajima S MesP1 and MesP2 are essential for the development of cardiac mesoderm. Development (2 000) 127:3215-26
11976685 Nishimura EK Dominant role of the niche in melanocyte stem-cell fate determination. Nature (2 002) 416:854-60

Pages

EMMA ID

EM:08395

Genetic Status

GMO

Background Strain Name

C57BL/6

Background Strain MGI ID

MGI:2159769

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