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Stock B6;129-Gt(ROSA)26Sor<tm1(CAG-Venus/GMNN,Cherry/CDT1)Jkn>/JknH

FESA Number

6899

Strain Name

B6;129-Gt(ROSA)26Sor<tm1(CAG-Venus/GMNN,Cherry/CDT1)Jkn>/JknH

Mutation Strain Type

Attribution

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Gt(ROSA)26Sor<tm1(CAG-Venus/GMNN,-Cherry/CDT1)Jkn> MGI:5645798 Gt(ROSA)26Sor MGI:104735 6

Phenotypic Description

The Fucci system was developed by fusing red- and green-emitting fluorescent proteins to the E3 ligase substrates, Cdt1 and Geminin. These fluorescent probes make it possible to distinguish between cells in the G1 or S/G2/M phases of the cell cycle in live cells/tissue (Sakaue-Sawano al 2008). Fucci2a is a bicistronic version of Fucci2 allowing Cre-mediated tissue-specific expression in mice (Mort, R et al 2014).

Publications

Displaying 11 - 20 of 88 Stock Publications
Pubmed ID Authors Title Journal
16950126 Sebzda E Syk and Slp-76 mutant mice reveal a cell-autonomous hematopoietic cell contribution to vascular development. Dev Cell (2 006) 11:349-61
21693582 Yeh JR Wnt5a is a cell-extrinsic factor that supports self-renewal of mouse spermatogonial stem cells. J Cell Sci (2 011) 124:2357-66
19131588 Ando S Bone marrow-derived cells are not the origin of the cancer stem cells in ultraviolet-induced skin cancer. Am J Pathol (2 009) 174:595-601
10591652 Cichowski K Mouse models of tumor development in neurofibromatosis type 1. Science (1 999) 286:2172-6
19653308 Hsu W Manipulating gene activity in Wnt1-expressing precursors of neural epithelial and neural crest cells. Dev Dyn (2 010) 239:338-45
15556998 Morroni M Reversible transdifferentiation of secretory epithelial cells into adipocytes in the mammary gland. Proc Natl Acad Sci U S A (2 004) 101:16801-6
21094155 Shibata M The mouse KRAB zinc-finger protein CHATO is required in embryonic-derived tissues to control yolk sac and placenta morphogenesis. Dev Biol (2 011) 349:331-41
22761943 Yeh JR Indirect effects of Wnt3a/?-catenin signalling support mouse spermatogonial stem cells in vitro. PLoS One (2 012) 7:e40002
15046721 Anthony TE Radial glia serve as neuronal progenitors in all regions of the central nervous system. Neuron (2 004) 41:881-90
21822279 Costello I The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation. Nat Cell Biol (2 011) 13:1084-91

Pages

EMMA ID

EM:08395

Genetic Status

GMO

Background Strain Name

C57BL/6

Background Strain MGI ID

MGI:2159769

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