Stock B6.129-Flrt3<tm1Rob>/RobH

FESA Number

6825

Strain Name

B6.129-Flrt3<tm1Rob>/RobH

Mutation Strain Type

Attribution

Institution name Depositor / Originator Name
University of Oxford Originator Retained
University of Oxford Depositor Retained

Phenotypic Description

Mouse embryos deficient in Flrt3 display defects in headfold fusion, definitive endoderm migration and a failure of the lateral edges of the ventral body wall to fuse, leading to cardia bifida. A small proportion of homozygous mutants survive gestation and develop as viable fertile animals (<3%). Heterozygous mice have no overt phenotype.

Publications

EMMA ID

EM:08316

Genetic Status

GMO

Background Strain Name

C57BL/6J

Background Strain MGI ID

MGI:3028467

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