Stock B6;129-Brca1<tm1Aash>/Aash

FESA Number


Strain Name


Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Targeted mutation IMSR - unclassified


Institution name Depositor / Originator Name
Institute of Cancer Research Originator Retained
Institute of Cancer Research Depositor Retained

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Brca1<tm1Aash> MGI:3706167 Brca1 MGI:104537 11

Phenotypic Description

No visible phenotype.

Orphanet Disorders

OrphaNet ID Name Url
168 829 Primary peritoneal carcinoma
1 331 Familial prostate cancer
213 524 Hereditary site-specific ovarian cancer syndrome
145 Hereditary breast and ovarian cancer syndrome
227 535 Hereditary breast cancer
1 333 Familial pancreatic carcinoma


Displaying 1 - 2 of 2 Stock Publications
Pubmed ID Authors Title Journal
17212342 McCarthy A A mouse model of basal-like breast carcinoma with metaplastic elements. J Pathol (2 007) 211:389-98
20804975 Molyneux G BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells. Cell Stem Cell (2 010) 7:403-17

Orphanet Categories

Rare abdominal surgical disease
Rare oncologic disease
Rare urogenital disease
Rare gynecologic or obstetric disease
Rare gastroenterologic disease




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