Stock B6;129-Apoe<tm1Bres> Lgals3<tm1Ftl>/CljH

FESA Number

2896

Strain Name

B6;129-Apoe<tm1Bres> Lgals3<tm1Ftl>/CljH

Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Targeted mutation IMSR - unclassified

Attribution

Institution name Depositor / Originator Name
University of Bristol Originator Retained
University of Bristol Depositor Retained

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Lgals3<tm1Ftl> MGI:2386938 Lgals3 MGI:96778 14
Apoe<tm1Bres> MGI:2137814 Apoe MGI:88057 7

Phenotypic Description

No overt phenotype reported.

Publications

Displaying 1 - 10 of 156 Stock Publications
Pubmed ID Authors Title Journal
25343273 Baek JH Galectin-3 activates PPAR? and supports white adipose tissue formation and high-fat diet-induced obesity. Endocrinology (2 015) 156:147-56
15361471 Iacobini C Galectin-3/AGE-receptor 3 knockout mice show accelerated AGE-induced glomerular injury: evidence for a protective role of galectin-3 as an AGE receptor. FASEB J (2 004) 18:1773-5
21573150 Oliveira FL Lack of galectin-3 disturbs mesenteric lymph node homeostasis and B cell niches in the course of Schistosoma mansoni infection. PLoS One (2 011) 6:e19216
1712312 Agarwal N Sequence analysis, expression and chromosomal localization of a gene, isolated from a subtracted human retina cDNA library, that encodes an insulin-like growth factor binding protein (IGFBP2). Exp Eye Res (1 991) 52:549-61
9555870 de Villiers WJ Macrophage phenotype in mice deficient in both macrophage-colony-stimulating factor (op) and apolipoprotein E. Arterioscler Thromb Vasc Biol (1 998) 18:631-40
14614151 Idel S A20, a regulator of NFkappaB, maps to an atherosclerosis locus and differs between parental sensitive C57BL/6J and resistant FVB/N strains. Proc Natl Acad Sci U S A (2 003) 100:14235-40
12569158 Lesnik P Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherogenesis. J Clin Invest (2 003) 111:333-40
1423598 Plump AS Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell (1 992) 71:343-53
11988491 Silence J Reduced atherosclerotic plaque but enhanced aneurysm formation in mice with inactivation of the tissue inhibitor of metalloproteinase-1 (TIMP-1) gene. Circ Res (2 002) 90:897-903
8962133 Weng W Dramatically decreased high density lipoprotein cholesterol, increased remnant clearance, and insulin hypersensitivity in apolipoprotein A-II knockout mice suggest a complex role for apolipoprotein A-II in atherosclerosis susceptibility. Proc Natl Acad Sci U S A (1 996) 93:14788-94

Pages

EMMA ID

EM:02060

Genetic Status

GMO

Background Strain Name

C57BL/6

Background Strain MGI ID

MGI:2159769

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