Stock B6.129-Anpep<tm1Afk>/AfkH
FESA Number
7353
Strain Name
B6.129-Anpep<tm1Afk>/AfkH
Mutation Strain Type
| Mutation Type | Mutation Subtype | Strain Type |
|---|---|---|
| IMSR - Targeted mutation - Knock out | IMSR - mutant stock |
Attribution
| Institution name | Depositor / Originator | Name |
|---|---|---|
| Unknown Institution | Originator | Retained |
| Unknown Institution | Depositor | Retained |
Gene/Allele Information
| Allele Name | Allele MGI ID | Gene Name | Gene MGI ID | Chromosome |
|---|---|---|---|---|
| Anpep<tm1Afk> | MGI:5582781 | Anpep | MGI:5000466 | 7 |
Phenotypic Description
No overt phenotype is seen in mice homozygous for Anpep<tm1aAfk>. However, a delay in mammary development was detected. Similar knock-outs for Anpep have shown a deficiency in tumour vascularisation. This was not assessed for this mutated allele. Heterozygotes had no detectable phenotype.
See PMID:22983824.
Publications
Displaying 1 - 1 of 1 Stock Publications
| Pubmed ID | Authors | Title | Journal |
|---|---|---|---|
| 22983824 | Kolb AF | Mammary gland development is delayed in mice deficient for aminopeptidase N. | Transgenic Res (2 013) 22:425-34 |
EMMA ID
EM:09063
Genetic Status
GMO
Background Strain Name
C57BL/6
Background Strain MGI ID
MGI:2159769
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