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Stock Antonia

FESA Number

2884

Strain Name

Antonia

Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Chemically Induced Mutation IMSR - unclassified

Attribution

Institution name Depositor / Originator Name
University of Oxford Originator Retained
University of Oxford Depositor Retained

Phenotypic Description

An ENU-induced mutation causing heritable anti-nuclear antibodies and variable proliferative and membranous glomerulonephritis with partial dominant phenotype and penetrance by 12-16 weeks of age. Lymphocyte populations appear grossly normal by flow cytometry and immunoglobulin levels.

Publications

EMMA ID

EM:02252

Production Information

ENU-derived mutant

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