Mutation Strain Type
|Mutation Type||Mutation Subtype||Strain Type|
|IMSR - Chemically Induced Mutation||IMSR - unclassified|
|Institution name||Depositor / Originator||Name|
|University of Oxford||Originator||Retained|
|University of Oxford||Depositor||Retained|
An ENU-induced mutation causing heritable anti-nuclear antibodies and variable proliferative and membranous glomerulonephritis with partial dominant phenotype and penetrance by 12-16 weeks of age. Lymphocyte populations appear grossly normal by flow cytometry and immunoglobulin levels.