Stock

FESA Number

1875

Strain Name

129S(Cg)-Foxh1<tm1Jlw>/H

Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Targeted mutation IMSR - mutant stock

Attribution

Institution name Depositor / Originator Name
University of Oxford Originator Retained
University of Oxford Depositor Retained

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Foxh1<tm1Jlw> MGI:2179442 Foxh1 MGI:1347465 15

Phenotypic Description

Homozygous lethal at day 8 of gestation.

Publications

Displaying 1 - 7 of 7 Stock Publications
Pubmed ID Authors Title Journal
21822279 Costello I The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation. Nat Cell Biol (2 011) 13:1084-91
11358869 Hoodless PA FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse. Genes Dev (2 001) 15:1257-71
25209250 Hou J A regulatory network controls nephrocan expression and midgut patterning. Development (2 014) 141:3772-81
17568773 Izzi L Foxh1 recruits Gsc to negatively regulate Mixl1 expression during early mouse development. EMBO J (2 007) 26:3132-43
19896480 McKnight KD Foxh1 and Foxa2 are not required for formation of the midgut and hindgut definitive endoderm. Dev Biol (2 010) 337:471-81
18331719 Silvestri C Genome-wide identification of Smad/Foxh1 targets reveals a role for Foxh1 in retinoic acid regulation and forebrain development. Dev Cell (2 008) 14:411-23
15363409 von Both I Foxh1 is essential for development of the anterior heart field. Dev Cell (2 004) 7:331-45

EMMA ID

EM:02525

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