Stock

FESA Number

6703

Strain Name

129P2-Gal<tm1Wyn>/WynH

Mutation Strain Type

Attribution

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Gal<tm1Wyn> MGI:2183172 Gal MGI:95637 19

Phenotypic Description

Developmental deficits in DRG and cholinergic neurons, absence of neuropathic pain, deficits in neuronal regeneration and neurite outgrowth and more severe disease in EAE model of MS and A-beta model of AD

Publications

Displaying 21 - 26 of 26 Stock Publications
Pubmed ID Authors Title Journal
12721371 Holmes FE Transgenic overexpression of galanin in the dorsal root ganglia modulates pain-related behavior. Proc Natl Acad Sci U S A (2 003) 100:6180-5
18463495 Hulse R Characterization of a novel neuropathic pain model in mice. Neuroreport (2 008) 19:825-9
11489302 Kehr J Microdialysis in freely moving mice: determination of acetylcholine, serotonin and noradrenaline release in galanin transgenic mice. J Neurosci Methods (2 001) 109:71-80
10762308 Kerr BJ Galanin knockout mice reveal nociceptive deficits following peripheral nerve injury. Eur J Neurosci (2 000) 12:793-802
11711881 Kerr BJ Endogenous galanin is required for the full expression of central sensitization following peripheral nerve injury. Neuroreport (2 001) 12:3331-4
11514086 Kerr BJ Endogenous galanin potentiates spinal nociceptive processing following inflammation. Pain (2 001) 93:267-77

Pages

EMMA ID

EM:08194

Genetic Status

GMO

Background Strain Name

129P2/OlaHsd

Background Strain MGI ID

MGI:2164147

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