Stock

FESA Number

2898

Strain Name

129.Cg-Tgm2<tm1Gml> Apoe<tm1Bres>/CljH[cc]

Mutation Strain Type

Attribution

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Apoe<tm1Bres> MGI:2137814 Apoe MGI:88057 7
Tgm2<tm1Gml> MGI:2180638 Tgm2 MGI:98731 2

Phenotypic Description

None.

Publications

Displaying 21 - 30 of 142 Stock Publications
Pubmed ID Authors Title Journal
14614151 Idel S A20, a regulator of NFkappaB, maps to an atherosclerosis locus and differs between parental sensitive C57BL/6J and resistant FVB/N strains. Proc Natl Acad Sci U S A (2 003) 100:14235-40
12569158 Lesnik P Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherogenesis. J Clin Invest (2 003) 111:333-40
1423598 Plump AS Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell (1 992) 71:343-53
11988491 Silence J Reduced atherosclerotic plaque but enhanced aneurysm formation in mice with inactivation of the tissue inhibitor of metalloproteinase-1 (TIMP-1) gene. Circ Res (2 002) 90:897-903
8962133 Weng W Dramatically decreased high density lipoprotein cholesterol, increased remnant clearance, and insulin hypersensitivity in apolipoprotein A-II knockout mice suggest a complex role for apolipoprotein A-II in atherosclerosis susceptibility. Proc Natl Acad Sci U S A (1 996) 93:14788-94
12205028 Bernassola F Role of transglutaminase 2 in glucose tolerance: knockout mice studies and a putative mutation in a MODY patient. FASEB J (2 002) 16:1371-8
23001131 Oh K Transglutaminase 2 exacerbates experimental autoimmune encephalomyelitis through positive regulation of encephalitogenic T cell differentiation and inflammation. Clin Immunol (2 012) 145:122-32
22469977 Alikhani N Mammary tumor growth and pulmonary metastasis are enhanced in a hyperlipidemic mouse model. Oncogene (2 013) 32:961-7
21041949 Feig JE LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression. J Clin Invest (2 010) 120:4415-24
9466986 Jeong Ts Increased sphingomyelin content of plasma lipoproteins in apolipoprotein E knockout mice reflects combined production and catabolic defects and enhances reactivity with mammalian sphingomyelinase. J Clin Invest (1 998) 101:905-12

Pages

EMMA ID

EM:02064

Genetic Status

GMO

Background Strain Name

129

Background Strain MGI ID

MGI:2160041

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