Stock

FESA Number

1589

Strain Name

129.Cg-Pax6<Sey> Tg(Hbb-b1)83Clo/WsH

Mutation Strain Type

Attribution

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Pax6<Sey> MGI:1856155 Pax6 MGI:97490 2
Tg(Hbb-b1)83Clo MGI:2655271 3

Phenotypic Description

Reiterated transgene is detectable by DNA in situ hybridisation.

Publications

Displaying 81 - 90 of 141 Stock Publications
Pubmed ID Authors Title Journal
21418559 Manuel MN The transcription factor Foxg1 regulates telencephalic progenitor proliferation cell autonomously, in part by controlling Pax6 expression levels. Neural Dev (2 011) 6:9
21264945 Ceruti S Expression of the new P2Y-like receptor GPR17 during oligodendrocyte precursor cell maturation regulates sensitivity to ATP-induced death. Glia (2 011) 59:363-78
23798316 Elso C A reciprocal translocation dissects roles of Pax6 alternative promoters and upstream regulatory elements in the development of pancreas, brain, and eye. Genesis (2 013) 51:630-46
7789273 Grindley JC The role of Pax-6 in eye and nasal development. Development (1 995) 121:1433-42
22071102 Karus M The extracellular matrix molecule tenascin C modulates expression levels and territories of key patterning genes during spinal cord astrocyte specification. Development (2 011) 138:5321-31
23622063 Mi D Pax6 exerts regional control of cortical progenitor proliferation via direct repression of Cdk6 and hypophosphorylation of pRb. Neuron (2 013) 78:269-84
23595746 Roy A LHX2 is necessary for the maintenance of optic identity and for the progression of optic morphogenesis. J Neurosci (2 013) 33:6877-84
9367432 Stoykova A Pax6-dependent regulation of adhesive patterning, R-cadherin expression and boundary formation in developing forebrain. Development (1 997) 124:3765-77
15269172 Waclaw RR The homeobox gene Gsh2 is required for retinoid production in the embryonic mouse telencephalon. Development (2 004) 131:4013-20
9363853 Quinn JC Genetic background effects on dental and other craniofacial abnormalities in homozygous small eye (Pax6Sey/Pax6Sey) mice. Anat Embryol (Berl) (1 997) 196:311-21

Pages

Orphanet Categories

Rare developmental defect during embryogenesis
Rare urogenital disease
Rare renal disease
Rare eye disease
Rare endocrine disease
Rare oncologic disease
Rare gynecologic or obstetric disease
Rare neurologic disease

EMMA ID

EM:01891

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