Stock

FESA Number

1589

Strain Name

129.Cg-Pax6<Sey> Tg(Hbb-b1)83Clo/WsH

Mutation Strain Type

Attribution

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Pax6<Sey> MGI:1856155 Pax6 MGI:97490 2
Tg(Hbb-b1)83Clo MGI:2655271 3

Phenotypic Description

Reiterated transgene is detectable by DNA in situ hybridisation.

Publications

Displaying 71 - 80 of 141 Stock Publications
Pubmed ID Authors Title Journal
10964956 Vitalis T Defect of tyrosine hydroxylase-immunoreactive neurons in the brains of mice lacking the transcription factor Pax6. J Neurosci (2 000) 20:6501-16
Lo CW Iontophoretic DNA injections and the production of transgenic mice Mouse Genome (1 992) 90:684-686
18701439 Carney RS Differential regulation of telencephalic pallial-subpallial boundary patterning by Pax6 and Gsh2. Cereb Cortex (2 009) 19:745-59
10704887 Dohrmann C Pax genes and the differentiation of hormone-producing endocrine cells in the pancreas. Mech Dev (2 000) 92:47-54
24355924 Gregory-Evans CY Postnatal manipulation of Pax6 dosage reverses congenital tissue malformation defects. J Clin Invest (2 014) 124:111-6
16866875 Kanakubo S Abnormal migration and distribution of neural crest cells in Pax6 heterozygous mutant eye, a model for human eye diseases. Genes Cells (2 006) 11:919-33
22220192 McBride DJ DNaseI hypersensitivity and ultraconservation reveal novel, interdependent long-range enhancers at the complex Pax6 cis-regulatory region. PLoS One (2 011) 6:e28616
Roberts RC Small-eyes, a new dominant mutant in the mouse. Genet Res (1 967) 9:121-122
8951061 Stoykova A Forebrain patterning defects in Small eye mutant mice. Development (1 996) 122:3453-65
19000783 Vogel T Expression of Leukaemia associated transcription factor Af9/Mllt3 in the cerebral cortex of the mouse. Gene Expr Patterns (2 009) 9:83-93

Pages

Orphanet Categories

Rare developmental defect during embryogenesis
Rare urogenital disease
Rare renal disease
Rare eye disease
Rare endocrine disease
Rare oncologic disease
Rare gynecologic or obstetric disease
Rare neurologic disease

EMMA ID

EM:01891

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