Stock 129.Cg-Pax6<Sey> Tg(Hbb-b1)83Clo/WsH

FESA Number

1589

Strain Name

129.Cg-Pax6<Sey> Tg(Hbb-b1)83Clo/WsH

Mutation Strain Type

Attribution

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Pax6<Sey> MGI:1856155 Pax6 MGI:97490 2
Tg(Hbb-b1)83Clo MGI:2655271 3

Phenotypic Description

Reiterated transgene is detectable by DNA in situ hybridisation.

Publications

Displaying 131 - 140 of 141 Stock Publications
Pubmed ID Authors Title Journal
8689689 Schedl A Influence of PAX6 gene dosage on development: overexpression causes severe eye abnormalities. Cell (1 996) 86:71-82
11493521 Tarabykin V Cortical upper layer neurons derive from the subventricular zone as indicated by Svet1 gene expression. Development (2 001) 128:1983-93
24698273 Zhang J V1 and v2b interneurons secure the alternating flexor-extensor motor activity mice require for limbed locomotion. Neuron (2 014) 82:138-50
10662634 Collinson JM Different roles for Pax6 in the optic vesicle and facial epithelium mediate early morphogenesis of the murine eye. Development (2 000) 127:945-56
18700968 Fotaki V Newly identified patterns of Pax2 expression in the developing mouse forebrain. BMC Dev Biol (2 008) 8:79
15031110 Heller RS The role of Brn4/Pou3f4 and Pax6 in forming the pancreatic glucagon cell identity. Dev Biol (2 004) 268:123-34
16364898 Landsberg RL Hindbrain rhombic lip is comprised of discrete progenitor cell populations allocated by Pax6. Neuron (2 005) 48:933-47
24814534 Pattabiraman K Transcriptional regulation of enhancers active in protodomains of the developing cerebral cortex. Neuron (2 014) 82:989-1003
8213068 Schmahl W Defects of neuronal migration and the pathogenesis of cortical malformations are associated with Small eye (Sey) in the mouse, a point mutation at the Pax-6-locus. Acta Neuropathol (1 993) 86:126-35
15758185 Tole S Selective requirement of Pax6, but not Emx2, in the specification and development of several nuclei of the amygdaloid complex. J Neurosci (2 005) 25:2753-60

Pages

Orphanet Categories

Rare developmental defect during embryogenesis
Rare urogenital disease
Rare renal disease
Rare eye disease
Rare endocrine disease
Rare oncologic disease
Rare gynecologic or obstetric disease
Rare neurologic disease

EMMA ID

EM:01891

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