Stock

FESA Number

1589

Strain Name

129.Cg-Pax6<Sey> Tg(Hbb-b1)83Clo/WsH

Mutation Strain Type

Mutation Type Mutation Subtype Strain Type
IMSR - Transgenic IMSR - unclassified

Attribution

Institution name Depositor / Originator Name
University of Edinburgh Originator Retained
University of Edinburgh Depositor Retained

Gene/Allele Information

Allele Name Allele MGI ID Gene Name Gene MGI ID Chromosome
Pax6<Sey> MGI:1856155 Pax6 MGI:97490 2
Tg(Hbb-b1)83Clo MGI:2655271 3

Phenotypic Description

Reiterated transgene is detectable by DNA in situ hybridisation.

Publications

Displaying 1 - 10 of 141 Stock Publications
Pubmed ID Authors Title Journal
22031545 Asami M The role of Pax6 in regulating the orientation and mode of cell division of progenitors in the mouse cerebral cortex. Development (2 011) 138:5067-78
15037575 Collinson JM Corneal development, limbal stem cell function, and corneal epithelial cell migration in the Pax6(+/-) mouse. Invest Ophthalmol Vis Sci (2 004) 45:1101-8
16766714 Fuccillo M Removal of Pax6 partially rescues the loss of ventral structures in Shh null mice. Cereb Cortex (2 006) 16 Suppl 1:i96-102
16122727 Heller RS Genetic determinants of pancreatic epsilon-cell development. Dev Biol (2 005) 286:217-24
16950124 Lei Q Wnt signaling inhibitors regulate the transcriptional response to morphogenetic Shh-Gli signaling in the neural tube. Dev Cell (2 006) 11:325-37
15733660 Philips GT Precocious retinal neurons: Pax6 controls timing of differentiation and determination of cell type. Dev Biol (2 005) 279:308-21
15229646 Schuurmans C Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways. EMBO J (2 004) 23:2892-902
1612585 Ton CC Small eye (Sey): cloning and characterization of the murine homolog of the human aniridia gene. Genomics (1 992) 13:251-6
15238450 Zimmer C Dynamics of Cux2 expression suggests that an early pool of SVZ precursors is fated to become upper cortical layer neurons. Cereb Cortex (2 004) 14:1408-20
22265416 Balaskas N Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube. Cell (2 012) 148:273-84

Pages

Orphanet Categories

Rare developmental defect during embryogenesis
Rare urogenital disease
Rare renal disease
Rare eye disease
Rare endocrine disease
Rare oncologic disease
Rare gynecologic or obstetric disease
Rare neurologic disease

EMMA ID

EM:01891

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